A Urinary Tract Infection (UTI) is an infection that damages the differentiated parts of the urinary tract. As per Ayurveda, there are three energies in the human body – Vatta, Kapha, and Pitta. UTI is caused due to a violation in the Pitta Dosha. In modern medical science, it depends upon the deterioration in the upper and lower part of the urinary tract. The deterioration of the upper part of the urinary tract is known as kidney infection (pyelonephritis), and the lower part, which is known as a bladder infection (cystitis). Mutravahasrotas are the urine carrying channels that begin with kidneys and ends with ureters (the passageways). The pathogenic reason behind this infection is Escherichia coli, fungi, Klebsiella, and Proteus spp. These bacteria enter the human bladder through the urethra, where they make it through the bowel. However, the carrier of this infection can be blood or lymph as well. The anatomy of women’s bodies always puts them at a higher risk of infection than men. Once the bacteria (E. coli) successfully attain their way to the bladder, they get affixed to the bladder walls and shape a biofilm (syntrophic union of microorganisms) that conveniently resists the reaction of the bodily immune. Hence, the medicines of Ayurveda and Pitta pacifying diet alter the vitiation in the Pitta dosh.